The Tickborne test reports results as 1-10 for "in control" antibodies, 11-20 for moderately elevated antibodies, and 21-30 for highly elevated antibodies.
Lyme Panel- Borrelia Burgdorferi
The Lyme panel reports results as positive or negative according to the CDC/IDSA Lyme Criteria or the Vibrant Alternative Lyme criteria.
Lyme IgM Interpretation
By CDC/IDSA criteria Lyme IgM is reported positive if VlsE1 or C6 peptide or WCS (Whole cell sonicate) is positive and two of the following three antigens are positive: 23-25kDa, 39kDa and 41kDa.
In the alternate criteria, IgM is reported positive if VlsE1 or C6 peptide or WCS (Whole cell sonicate) is borderline or positive and any two of the following antigens are borderline or positive: 23-25kDa, 31kDa, 34kDa, 39kDa, 41kDa and 83-93kDa. This interpretation is based on internal validation studies.
Lyme IgG Interpretation
By CDC criteria Lyme IgG is reported positive if VlsE1 or C6 peptide or WCS (Whole cell sonicate) is positive and any five of the following ten antigens are positive: 18kDa, 23-25kDa, 28kDa, 30kDa, 39kDa, 41kDa, 45kDa, 58kDa, 66kDa and 83-93kDa.
In the alternate criteria, IgG is reported positive if VlsE1 or C6 peptide or WCS is borderline or positive and two of the following antigens are borderline or positive: 18kDa, 23-25kDa, 28kDa, 30kDa, 31kDa, 34kDa, 39kDa, 41kDa, 45kDa, 58kDa, 66kDa and 83-93kDa. The alternate criteria are based on internal validation studies.
Clinical Correlation is Required
As with all testing, results should be interpreted in light of a patient’s history, physical examination, and/or results of other diagnostic testing.
