The short answer is yes, celiac disease can be ruled out >99.0% of the time in this case. Negative tests for both HLA-DQ2 and HLA-DQ8 genes make celiac disease highly unlikely. Read more at https://nationalceliac.org/celiac-disease-questions/celiac-genes/.
If a person does not have the celiac genes, can celiac disease be ruled out?
Adair
