Will high-dose biotin supplementation interfere with Vibrant's Micronutrient test results?

Yes. Excess biotin in patients’ blood samples can interfere with immunoassays because many use biotin as part of the testing methodology. High dose biotin supplementation (>5 mg/day) may lead to falsely elevated vitamin D25-OH, vitamin B12, and folate results. Additionally, high dose biotin may lead to falsely lowered ferritin results. As it is difficult for the laboratory to identify biotin-containing specimens, people taking high dose biotin should discontinue biotin supplementation at least 12 hours (or preferably 24-48 hours) prior to specimen collection.