When is the best time to test Total Immunoglobulins in relation to Tickborne testing?

This is up to the provider’s discretion. Here are two options. (1) Order Total Immunoglobulins. Wait for test results. If Total Immunoglobulin levels are OK, then order Tickborne test. If Total Immunoglobulin levels are low or high, the provider may not want to test Tickborne as the results may be falsely lower or falsely higher. (2) Order Tickborne test with the free Total Immunoglobulins add-on. If Total Immunoglobulin levels are OK, then interpret Tickborne test results like normal. If Total Immunoglobulin levels are low or high, Tickborne results may be falsely lower or falsely higher and it may require be a more complicated interpretation. Keep in mind that Total Immunoglobulin levels can change over time.