Are Anti-purkinje and anti-Yo interconnected?

Yes. Both Anti-Purkinje and Anti-Yo antibodies are  part of the Brain Autoimmunity panel. Anti-Yo antibodies are found in the serum of patients with neurologic paraneoplastic syndromes and reported to have activity against Purkinje cells of the cerebellum. Learn more at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291278

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