Please consider the studies below that provide evidence that elimination diets based on IgG results significantly reduced symptoms.
- Perhaps the best starting place in the review of food reactions testing is this study by Mullin, et al. (2010) Testing for Food Reactions: The Good, the Bad, and the Ugly
“Of the results obtained, testing for immunoglobulin E (IgE)–mediated food allergy was best represented in PubMed. IgE-based testing continues to be the gold standard for suspected food allergies. Among modalities used by many conventional and alternative practitioners, immunoglobulin G (IgG)–based testing showed promise, with clinically meaningful results. It has been proven useful as a guide for elimination diets, with clinical impact for a variety of diseases. Mediator release testing and antigen leukocyte cellular antibody testing were only represented on consumer sites.” This article cites several studies prior to 2010 that provide support for elimination diets. - (2011) Randomised controlled trial of food elimination diet based on IgG antibodies for the prevention of migraine like headaches
“Use of the ELISA test with subsequent diet elimination advice did not reduce the disability or impact on daily life of migraine like headaches or the number of migraine like headaches at 12 weeks but it did significantly reduce the number of migraine like headaches at 4 weeks.” - (2012) IgG-Based Elimination Diet in Migraine Plus Irritable Bowel Syndrome
“Our findings indicate that food elimination based on IgG antibodies in migraine patients who suffer from concomitant IBS may effectively reduce symptoms from both disorders with possible positive impact on the quality of life of the patients as well as potential savings to the health-care system.” - (2013) Treating Irritable Bowel Syndrome with a Food Elimination Diet Followed by Food Challenge and Probiotics
“These data demonstrate that identifying and appropriately addressing food sensitivity in IBS patients not previously responding to standard therapy results in a sustained clinical response and impacts on overall well being and quality of life in this challenging entity.” - (2017) Food-Specific IgG Guided Elimination Diet; A Role in Mental Health?
“There is an increasing body of literature that links diet and the composition of the gut microbiome to mental health disorders, but, so far, very little about what specific targeted dietary changes are needed to help [54]. Whether food-specific IgG-guided elimination dietary changes could fulfil such a role, directly or indirectly, has yet to be evidenced fully, however, the new paradigm linking leaky gut, food-specific IgG, inflammation and mental health is both interesting and encouraging in helping our understanding [5]. Much of the focus on a role for food-specific IgG antibodies in mental health disorders has been on gliadin, wheat, yeast and milk, particularly in ASD and schizophrenia. This approach has now been broadened out to include testing for IgG reactions to a wide range of food proteins that are reflective of a typical diet. The important point here is that dietary intervention, on this basis, is personalised; dependent on specific tailored foodIgG test results, providing a unique targeted approach, and this makes sense immunologically. What is clear is that restoration and maintenance of healthy intestinal, and blood brain, barriers, and the composition of the gut microbiota, are key to improved health, and dietary changes based on IgG-guided elimination diet show promise as a viable intervention strategy” - (2018) Gut Microbiota, IgG-Guided Elimination Diet and Sports Performance
“Studies looking at the impact of food intolerance and the use of a personalised IgG-guided elimination diet on sports performance include one trial involving first team members from top rugby league club Wigan Warriors in the UK. After 3 months of supported dietary changes, 67% evidenced performance improvement as a direct result of their new diet [16]. Another study which utilised an elimination diet based on a food intolerance test, showed significantly improved health, body composition and faster lowering of heart rate after cardiopulmonary testing in a group of professional athletes. In addition, those from football and volleyball athletic teams showed improvements in concentration and memory after IgG-guided elimination diet after just 2 weeks of dietary changes [18]. In 2012, Lewis et al. [9] published a study that looked at the effect of eliminating immunologically reactive foods from the diet of overweight individuals. Participants lost, on average, 5kg in weight and 8cm in waist circumference over a 90 day period. In addition to the positive changes associated with body composition there was a significant drop in diastolic blood pressure and substantial improvements in both physical and mental quality of life.” - (2019) Effects of Diet Based on IgG Elimination Combined with Probiotics on Migraine Plus Irritable Bowel Syndrome
In summation, we provide the first clinical evidence that IgG elimination diet combined with probiotics may be beneficial to migraine plus IBS. Future work should uncover the potential mechanism of how it affects pathophysiology of migraine. - (2021) IGG FOOD ANTIBODY GUIDED ELIMINATION-ROTATION DIET WAS MORE EFFECTIVE THAN FODMAP DIET AND CONTROL DIET IN THE TREATMENT OF WOMEN WITH MIXED IBS – RESULTS FROM AN OPEN LABEL STUDY
“Based on the results of this open study it was found that the different dietary intervention in the treatment of patients with IBS-M was unlikely effective. The G2-IP IgG based elimination rotation-diet demonstrating a significant overall superior result compared to the others.”
