What tests are recommended for Restless Leg Syndrome (RLS)?

Organic Acids Test – To assess mitochondrial function, neurotransmitter metabolism, and oxidative stress.

  • Dopamine metabolites (HVA/DOPAC ratio) – To evaluate dopamine turnover, as dopamine dysregulation is central to RLS.
  • Lactic acid & Pyruvic acid – To check for mitochondrial dysfunction, which can contribute to muscle fatigue and movement disorders.


Total Toxin Burden Panel – To detect neurotoxic exposures that may impair dopamine function.

  • Mercury, lead, and thallium can contribute to neurotoxicity and RLS symptoms.
  • Mycotoxins from mold exposure can trigger inflammation in the nervous system.


Neural Zoomer Plus – To evaluate neurological autoimmunity and inflammation that may contribute to movement disorders.

Micronutrient Panel – To assess deficiencies in key nutrients involved in muscle and nerve function, such as:

  • Iron & Ferritin – Low ferritin is strongly linked to RLS.
  • Magnesium – Essential for muscle relaxation and neurotransmitter function.
  • B Vitamins (B6, B12, Folate) – Involved in dopamine metabolism and nerve health.
  • Vitamin D – Deficiency has been associated with worsened RLS symptoms.
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