Important Guidance:
To identify your “normal” cardiometabolic profile, maintain your routine diet, medications, and supplements unless specifically instructed otherwise by your healthcare provider. This ensures results reflect your usual physiological state. Collect the first-morning urine sample upon waking. Do not consume food or drink (except water) for at least 8 hours prior to collecting.
Test Interference:
Test interference occurs when a medication or supplement alters the sample or test reagents, potentially causing inaccurate results (e.g., false positive or false negative).
Biological Effects:
Without interfering with the test, some substances can influence your body’s biomarkers, affecting your results by increasing or decreasing the biomarker. However, biological effects do not interfere with test performance, accuracy, or validity. Results will be accurate as measured.
RECOMMENDED: Preparing for the Test to Avoid Test Interference
- Medications: Do not discontinue any prescribed medication without your healthcare provider’s instruction. Avoid antibiotics or corticosteroids for 72 hours before collection.
- Hydration: Ensure adequate hydration by drinking 8 glasses of water per day for 2-3 days before the test. On the collection day, do not drink more than 8 oz of water 1 hour prior to urine collection.
OPTIONAL: Preparing for the Test to Avoid Biological Effects
- Diet: Avoid foods high in antioxidants such as berries, leafy greens, nuts, caffeine, cocoa, and seeds. Refrain from consuming alcohol and caffeine for 48 hours before collection.
- Supplements: Avoid use of biotin supplements > 5,000 mcg (5 mg)/day, high dose antioxidant or anti-inflammatory supplements (e.g., vitamin A > 1,000 IU/day, beta-carotene > 5,000 IU/day, vitamin C > 1,000 mg/day, vitamin E > 400 IU/day, alpha-lipoic acid, selenium > 200 mcg/day, zinc > 15 mg/day, fish oil > 2,000 IU/day, CoQ10 > 100 mg/day, and curcumin, resveratrol, ginger, quercetin, or Boswellia doses > 250 mg/day) for 72 hours before collection. Consult your health care provider before stopping any prescribed supplements.
- Environmental Factors: Avoid intense physical exercise and exposure to environmental pollutants (e.g., cigarette smoke, exhaust fumes) 24 hours before the test.
Sample Collection: WHEN TO COLLECT
- Avoid collection: Avoid collecting Urine if you have active bleeding or if you are menstruating.
- Fasting: Fast 8 hours prior to blood collection (only water is allowed). Avoid alcohol and high-fat meals 24 hours before the test.
- Collection Timing: Schedule your blood draw in the morning after an overnight fast of at least 8 hours. Collect the first-morning urine sample upon waking.