It is unknown how long CdtB antibodies and vinculin antibodies will persist after an infectious enteritis. A systematic review and meta-analysis found that more than 10% of individuals with infectious enteritis later develop irritable bowel syndrome (IBS). The overall risk of developing IBS is 4.2 times higher in individuals with a history of infectious enteritis compared to individuals without a history of infectious enteritis. There was 10.1% prevalence of IBS at 12 months after infectious enteritis. That number increased to 14.5% prevalence of IBS when testing more than 12 months after infectious enteritis. Studies have examined post-infectious IBS onset within 12 months, within 13-59 months, and greater than 60 months (5 years) after the infectious event. Prevalence of post-infectious IBS depends upon the pathogen(s) involved, geographic location, clinically suspected or laboratory-proven enteritis, time of medical assessment following the infectious enteritis, and the criteria used to define IBS. Some studies report a decline in prevalence of IBS over time since the infectious event, whereas others report an increase in prevalence of IBS over time since the infectious event.
If Vibrant's Candida + IBS Profile provides insight into a past infectious gastroenteritis event, how many years back could the event have occurred?
Adair